Figure 4: Effects of mutations on dimerization of LXRα with PPARα. Cy3-labeled PPARα was titrated
against increasing concentrations of unlabeled LXRα in the absence of ligand. Representative
curves from fluorescence binding experiments are shown for binding of each LXRα mutant
to PPARα. At least three independent experiments were performed for each analysis.
Kd values represent means ± the standard error.
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