Table 7: Some Postulated PPAR Endogenous Ligands a.


PPAR α PPAR β/ δ PPAR γ

Endocannabinoids All trans retinoic acid Endocannabinoids
8-Hydroxyeicosatetraenoic acid (8-HETE) Arachidonic acid Farnesylpyrophosphates
Leukotrienen B4 Docahexanoic acid 15-Hydroxyeicosatetraenoic acid (15-HETE)
Oleoylethanolamide 4-Hydroxynonenal 13-Hydroxyoctadecadienoic acid (13-HODE)
Oxidized phospholipids Prostacyclin 5-Hydroxyindole acetate
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatocholine Linoleic acid 5-Methoxyindole acetate Nitro derivatives of unsaturated fatty acids Nitrolinoleic acid

a[301 , 302].