Figure 1: Multiple functions of RORs in lymphocyte development. A. Roles of RORγt in the development of Th17 cells, γδ-17 T cells, lymphoid tissue inducer (LTi) cells and innate lymphoid cells 3 (ILC3) cells. (B) Role of RORα in the development of ILC2 cells. RORα has also a role in the regulation of Th17 cells.