Figure 2: Effect of 15d-PGJ2 on cytokines release. BMDC were subjected to pretreatment with 15d-PGJ2 (1, 5, or 10μM) for 1 hour, followed by LPS stimulation. After 24 hours of stimulation, the culture supernatant was harvested and the levels of IL12p40 (a), IFN-γ(b, TNF-α(c), IL-1β(d), and IL-10 (e) were detected through ELISA assay. Data are the mean ± SD and are triplicate representative. #P<0.05 medium group compared with medium + LPS group. *P<0.05 medium + LPS group compared with 15d-PGJ2 + LPS group.