Figure 7: Interaction between virtual screen hit compounds
(♦H6036, ▪compound 3, ▴triiodothyronine) and VDR. (A)
Hit compound inhibition of the interaction between SRC2-3 and VDR
in the presence of VDR agonist LG190178. (B) Association of
VDR-LBD and SRC2-3 in the presence of hit compounds. (C) Structure
and generation of NR ligands.
|
|