Figure 7: Interaction between virtual screen hit compounds (♦H6036, ▪compound 3, ▴triiodothyronine) and VDR. (A) Hit compound inhibition of the interaction between SRC2-3 and VDR in the presence of VDR agonist LG190178. (B) Association of VDR-LBD and SRC2-3 in the presence of hit compounds. (C) Structure and generation of NR ligands.