Table 1: Effect of dexamethosone on serum liver biochemical indices of cyclophosphamide-treated rats.


Treatments AST(U/L) ALP(U/L) ALT(U/L) LDH(U/L) GGT(U/L) TB(g/dL) CB(g/dL)

CONTROL 32.0 ± 2.08a 34.0 ± 2.11a 35.3 ± 3.03a 37.8 ± 3.05a 13.5 ± 1.65a 4.52 ± 0.19a 3.63 ± 0.19a
DEXA 31.3 ± 2.11a 33.8 ± 2.25a 31.8 ± 3.17a 35.3 ± 3.32a 12.8 ± 1.09a 4.50 ± 0.29a 3.57 ± 0.19a
CP 121.5 ± 14.0c 128.5 ± 13.3c 115.4 ± 12.4c 120.5 ± 10.2c 49.3 ± 4.29c 19.3 ± 1.25c 18.3 ± 1.35c
DEXA+CP (Post) 85.5 ± 7.90d π 81.3 ± 8.35d π 79.0 ± 7.87d π 80.8 ± 8.03d π 34.3 ± 3.18d π 15.0 ± 1.27d π 14.0 ± 1.36d π
CP+DEXA (Cotr) 62.3 ± 6.21e # 61.0 ± 6.96e # 56.5 ± 4.41e # 61.8 ± 5.18e # 23.5 ± 2.25e # 10.5 ± 0.53e # 10.5 ± 0.65e #
CP+DEXA (Pre) 40.8 ± 3.37f * 52.8 ± 4.32f * 41.8 ± 3.44f * 51.5 ± 5.45f * 17.0 ± 1.13f * 7.54 ± 0.65f* 6.88 ± 0.48f *

Data presented as mean ± SEM, n = 6, CP: Cyclophosphamide, DEXA: Dexamethasone, Post: Post-treatment, Cotr: Co-treatment, Pret: Pre-treatment, AST: Aspartate aminotransferase, CB: Conjugated bilirubin, GGT: Gama glutamyl transferase, ALT: Alanine aminotransferase, LDH: Lactate dehydrogenase, TB: Total bilirubin, ALP: Alkaline phosphatise. Values with different alphabets down the column differ at p < 0.05, π p < 0.05 in comparison to CP, #p < 0.01 in comparison to CP, *p < 0.001 in comparison to CP