Figure 4: Shows photos of substantia nigra animals of control group 1(a,b), and that treated with reserpine 2 (a,b,c,d) where (1a) showed swollen perikaryon cells with short shrunken primary dendrites arrow (H&EX200) (1b) pyramidal or ovoid neuronal cells arrow (H&EX400), 2(a,b) showed neurodegeneration and necrosis of nigral neurons arrow (H&E X200) (2c) showed granular, pale-staining eosinophilic Lewy bodies(H&EX400) (2d) showed neuronal death, extracellular deposit Lewy bodies (H&E X400).