Figure 3: A: Photomicrograph of retina section of non-diabetic rat treated with PEG+H2O for 21 days, showing normal histo-architectural retinal layers with rods and cones (RC), outer nuclear layer (ONL), inner nuclear layer (INL), ganglion cell layer (GCL) and optic nerve fibers (ONF) H&E × 100, B: Photomicrograph of retina section of diabetic rat treated with PEG+H2O 21 days, showing distortion of the retinal layers (RD) H&E × 100, C: Photomicrograph of retina section of diabetic rat treated with glimepiride at 8 pm for 21 days, showing slight necrosis of the rods and cones (RC) and outer layer cells (ONL) H&E × 100, D: Photomicrograph of retina section of diabetic rat treated with glimepiride 8 pm and nifedipine 8 pm for 21 days, showing slight necrosis of the inner (INL) and outer layer (ONL) cells H&E × 100, E: Photomicrograph of retina section of diabetic rat treated with glimepiride 8 pm and nifedipine 8 am for 21 days, showing normal retinal layers with rods and cones (RC), outer nuclear layer (ONL), inner nuclear layer (INL), ganglion cell layer (GCL) and optic nerve fibers (ONF) H&E × 100.