Cysteine Protease Inhibitors from the Methanol Extract of the Root Bark of

Table 5: Changes in pack cell volume of Mice infected with P. berghei and treated with cysteine protease inhibitors of S. longepedunculata.


Treatment (/kg)	PCV (%)		Change (%)

	D0	D4
CPI (34 mg)	45.5 ± 3.87	47.50 ± 3.42 ^*	+2.11
CPI (23 mg)	44.25 ± 2.63	45.25 ± 2.50 ^*	+2.20
CPI (11 mg)	43.00 ± 2.58	46.75 ± 2.99 ^*	+8.02
Normal Saline (10 mL)	41.4 ± 3.44	37.4 ± 2.41	-10.7

Data presented are means ± SD and analysed using one way ANOVA followed by Dunnett's post hoc test. Values with the superscript ^* differs significantly ( p≤0.05) from the normal saline group within the same column; CPI = Cysteine protease inhibitors, D0 = First-day of drug administration, D4 = Fourth-day of drug administration.