Table 4: Changes in body weight of Mice infected with P. berghei and treated with cysteine protease inhibitors of S. longepedunculata.


Treatment (/kg) Weight (g) Decrease (%)

D0 D4
CPI (34 mg) 20.75 ± 4.92 18.25 ± 4.50 12.04
CPI (23 mg) 19.75 ± 2.99 17.25 ± 2.06 12.65
CPI (11 mg) 19.25 ± 1.26 17.50 ± 1.29 9.09
Artemether (2 mg) 20.25 ± 2.06 18.70 ± 2.31 7.65
N/S (10 mL) 19.4 ± 2.61 17.8 ± 2.68 8.24

Data presented are means ± SD and analysed using one way ANOVA. Values with the superscript * differs significantly ( p 0.05) from the normal saline group within the same column; CPI = Cysteine protease inhibitors, N/S = Normal Saline, D0 = First-day of drug administration, D4 = Fourth-day of drug administration.