Figure 3: Effects of SOF and DAC on CCl4 induced liver fibrosis by Masson's trichrome staining: Liver tissues from Control group (A) showing no collagen deposition. Liver tissues from CCl4 treated rats for 2 and 6 weeks (Figure 3- B&C) showing heavy deposition of collagen fibers appeared as light blue areas. Liver sections from SOF 20 mg/kg/day (Figure 3D), DAC (30 mg/kg/day) (Figure 3-E) and a combination of both drugs (Figure 3-F) treated rats showed minimal collagen deposition within tissues. Dark blue arrows showed the areas of collagen deposition. The original microscopic magnification was 40×.