Table 2: Effects of isoquercetin and or estrogen on dopamine, norepinephrine and serotonine levels in ovariectomized rats.


Treatment Parameter

Dopamine (ng/g wet tissue) Nor epinephrine (ng/g wet tissue) 5-HT (ng/g wet tissue)
Control 610 ± 10.2 78 ± 2.1 121 ± 10.1
Sham 650 ± 11.3 68 ± 3.3 205 ± 8.2
OVX 390 a, b ± 9.1 42 a, b ± 2.3 101 a, b ± 9.1
OVX + Isoqurcitrin 480 a, b, c ± 6.8 58 a, b, c ± 4.1 135 a, b, c ± 7.6
OVX + Estrogen 495 a, b, c ± 12.1 56 a, b, c ± 2.8 168 a, b, c, d ± 5.8
OVX + Isoqurcitrin + Estrogen 560 a, b, c, d, e ± 13.4 66 a, b, c, d, e ± 4.9 178 a, b, c, d ± 3.7

Data presented are means ± SEM. (n = 8).

aP < 0.05; significantly different from control group.

bP < 0.05; significantly different from OVX group. ANOVA followed by Tukey-Kramer post hoc test .

a: significant difference from control group.

b: significant difference from sham group.

c: significant difference from ovx (ovariectomized) non treated group.

d: significant difference from ovx (ovariectomized) isoquercetin treated group.

e: significant difference from ovx (ovariectomized) estrogen treated group.