Assessment of the Effect of HMGCR Variant Alleles on Response to Atorvastatin Treatment in Type 2 Diabetic Egyptian Patients

Table 3: Comparison of statin response according to genotyping and allele frequency.


	Total (n = 96)		Response				χ ²	P

		Non responder (n = 60)		Responder (n = 36)
	No.	%	No.	%	No.	%
Genotyping
CC	14	14.6	7	11.7	7	19.4	1.098	^MCp= 0.90
CT	28	29.2	18	30.0	10	27.8
TT	54	56.3	35	58.3	19	52.8
Allele
C	56	29.2	34	27.1	22	30.6	0.260	0.61
T	136	70.8	86	72.9	50	69.4	0.260	0.61

χ ²: Chi square test
MC: Monte Carlo
C: Normal allele.
T: Abnormal allele: where SNP is present
CC: Homozygous normal.
CT: Heterozygous abnormal.
TT: Homozygous abnormal.