Table 4: Effect of 4-aminopyridine (0.5, 1, 2, and 4 mg/kg/s.c) (Kv channel blocker) with diclofenac (10 mg/kg/i.p.) in the maximal electroshock seizure test in mice.
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| Diclofenac (10mg/kg,i.p)+4-aminopyridine(0.5,1,2 mg/kg/s.c) | Percentage of convulsion in (MES) model |
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| 0.5 mg/kg/s.c | 66.7% |
| 1 mg/kg/s.c | 83.3% |
| 2 mg/kg/s.c | 100% |
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