Figure 1: Effects of pioglitazone (30mg/kg/day), irbesartan (30mg/kg/day), and their combination in large and small doses on serum levels of IL-6 (ng/ml) and NO (umol) in streptozotocin induced diabetic nephropathy in rats. a: Significant difference from control group. b: Significant difference from diabetic group. c: Significant difference from irbesartan group. d: Significant difference from pioglitazone group.