Figure 1: Schematic illustration of mineralocorticoid receptor-mediated signaling pathways particularly in neoplastic cells. Ant, mineralocorticoid receptor antagonist; AR, androgen receptor; C, corticosteroid; Co-R, co-regulator; G, glucocorticoid; GR,glucocorticoid receptor; GRE, glucocorticoid response element; HRE; hormone response element; HSP, heat shock protein; MR,mineralocorticoid receptor; Spi, spironolactone.