|Figure 10: Proposed alternate binding cavities in SRs. A) PBS1 cavity (gray) in AR identified
showing adjacency to the LBP with DHT bound . B) Proposed binding cavity (gray)
for DBT in GR,
also adjacent to the dex-bound LBP. DBT co-binds with dex, but rearrangement of ASN564
potentially destabilizes bound dex .