Table 1: The sub-cellular localization of the members of the human nuclear receptor superfamily. The predictions made by the prediction methods and the evidences drawn after referring the available experimental observations have been tabulated here.


S.No. Name and Abbreviation Prediction from ngLOC Prediction from Hum-mPLoc-3.0 Experimental observations Concluding remarks

1. Dosage-sensitive sex reversal, adrenal hyperplasia critical region, on chromosome X, gene 1/ DAX1 NUC & CYT NUC NUC & CYT NUC & CYT
2 Small heterodimer partner/ SHP NUC NUC NUC NUC
3 Thyroid hormone receptor-α/ TRα NUC NUC NUC NUC
4 Thyroid hormone receptor-β/ TRβ NUC NUC NUC NUC
5 Retinoic acid receptor-α / RARα NUC & CYT NUC NUC & CYT NUC & CYT
6. Retinoic acid receptor-β / RARβ NUC & CYT NUC NUC & CYT NUC & CYT
7. Retinoic acid receptor-γ / RARγ NUC NUC NUC & CYT NUC & CYT
8. Peroxisome proliferator- activated receptor-α / PPARα NUC NUC NUC NUC
9. Peroxisome proliferator- activated receptor-β/δ / PPARβ/δ NUC NUC NUC NUC
10. Peroxisome proliferator- activated receptor-γ / PPARγ NUC NUC NUC/CYT NUC/CYT
11. Rev-erbAα / Rev-erbAα NUC NUC NUC NUC
12. Rev-erbAβ / Rev-erbAβ NUC NUC NUC NUC
13. RAR-related orphan receptor-α / RORα NUC NUC NUC NUC
14. RAR-related orphan receptor-β / RORβ NUC NUC NUC NUC
15. RAR- related orphan receptor-γ /RORγ NUC NUC NUC & CYT NUC & CYT
16. Liver X receptor-α / LXRα NUC NUC NUC NUC
17. Liver X receptor-β / LXRβ NUC NUC NUC NUC
18. Farnesoid X receptor / FXR NUC NUC NUC NUC
19. Vitamin D receptor / VDR NUC NUC NUC & CYT NUC & CYT
20. Pregnane X receptor / PXR NUC NUC NUC NUC
21. Constitutive androstane receptor / CAR NUC NUC NUC & CYT NUC & CYT
22. Hepatocyte nuclear factor-4-α / HNF4α NUC NUC NUC NUC
23. Hepatocyte nuclear factor-4-β / HNF4β NUC NUC NUC NUC
24. Retinoid X receptor-α/ RXRα NUC NUC NUC NUC
25. Retinoid X receptor-β/ RXRβ NUC NUC NUC NUC
26. Retinoid X receptor-γ / RXRγ NUC NUC NUC NUC
27. Testicular receptor 2/ TR2 NUC NUC NUC NUC
28. Testicular receptor 4/ TR4 NUC NUC NUC NUC
29. Homologue of Drosophila tailless gene / TLX NUC NUC NUC NUC
30. Photoreceptor cell specific nuclear receptor / PNR NUC NUC NUC NUC
31. Chicken ovalbumin upstream promoter transcription factor 1/ COUP-TF1 NUC NUC NUC NUC
32. Chicken ovalbumin upstream promoter transcription factor 2/ COUP-TF2 NUC NUC NUC NUC
33. V-erbA-related/ EAR-2 NUC NUC NUC NUC
34. Estrogen receptor-α / ERα NUC NUC NUC NUC
35. Estrogen receptor-β / Erβ NUC NUC NUC & CYT NUC & CYT
36. Estrogen-related receptor-α/ ERRα NUC NUC NUC NUC
37. Estrogen-related receptor-β/ ERRβ NUC NUC NUC NUC
38. Estrogen-related receptorγ-/ ERRγ NUC NUC NUC NUC
39. Glucocorticoid receptor / GR NUC & CYT NUC CYT CYT
40. Mineralocorticoid receptor / MR NUC NUC NUC & CYT NUC & CYT
41. Progesterone receptor / PR NUC & CYT NUC NUC NUC
42. Androgen receptor / AR NUC NUC CYT CYT
43. Nerve Growth Factor 1B/ Growth factor inducible immediate early gene nur 77/ NGFIB/ Nur77 NUC NUC NUC NUC
44. Nuclear receptor related 1/ NURR1 NUC NUC NUC NUC
45. Neuron-derived orphan receptor 1/ NOR 1 NUC NUC NUC NUC
46. Steroidogenic factor 1/ SF1 NUC NUC NUC NUC
47. Liver receptor homolog-1/ LRH-1 NUC NUC NUC NUC
48. Germ cell nuclear factor/ GCNF NUC NUC NUC NUC