Table 1: Exposure of Amino Acid Residues Predicted at LXRα Interface predicted using InterProSurf Protein-Protein Interaction Server (http://curie.utmb.edu/prosurf.html). Crystal structure of the protein complex of LXRα-RXRβ (PDB 1UHL) was analyzed to predict potential interface regions on the surface of LXRα protein using the probe radius of 1.4 A .


Amino Acid Residue Residue Number Monomer Area Complex Area Change in Accessible Surface Area

H 383 106 67 39
E 387 79 15 64
H 390 83 39 44
R 415 93 17 76