Figure 2: Apoptosis in testicular tissue assessed by the percentage of testicular area immunostained with caspase-3 (brown color). (a) Control group, (b) Methotrexate group (20 mg/kg), (c) Ginseng (500 mg/kg/day) + Methotrexate (20 mg/kg) group, (d) Ginseng nanoparticles (250 mg/kg/day) + Methotrexate (20 mg/kg) group, (e) Ginseng nanoparticles (125 mg/kg/day) + Methotrexate (20 mg/kg) group.