Figure 5: Effect of venlafaxine and/or cysteamine on brain-derived neurotrophic factor protein levels (pg/ml) (a). TrkB gene expression (fold of change) (b) in CORT-induced anxiety/depression mouse model. Values are mean ± SE (n = 8), analyzed by one-way ANOVA followed by Dunnett's multiple comparisons post hoc test. *P < 0.05 versus vehicle group, #P < 0.05 versus CORT group. BDNF: brain-derived neurotrophic factor, CORT: corticosterone, Ven low: Venlafaxine 10 mg/kg/day, Ven high: Venlafaxine 20 mg/kg/day, Cys: Cysteamine 150 mg/kg/day.