Table 3: The effect of diacerein (5, 10mg/kg) pretreatment on hepatic caspase-3 and cytochrome-c levels in IR liver injury in rats.


Groups Caspase-3 (ng/g) tissue Cytochrome-c (ng/mg) tissue

Sham 2.45 ± 0.13 69 ± 1.02
IR 18.47 ± 0.8 * 179 ± 2.54 *
Diacerein-SD 17.99 ± 0.7 # 172 ± 1.67 #
Diacerein-LD 4.65 ± 0.8 $ 73 ± 2.35 $
Data represent mean ± S.E.M.

*p<0.05 compared with sham group, # non-significant difference compared with IR group, $ p < 0.05 compared with IR group.