Figure 3: Representative NF-κB (p65) immunohistochemistry photomicrographs of different groups (magnification 400x). (a) Sham group showed negative expression of NFκp-p65. (b) IR group showed strong positive expression (black arrows). (c) Diacerein-SD group showed strong positive staining (black arrows). (d) Diacerein-LD group showed minimal staining for protein expression. The staining when quantified. Data shown in (e) is mean ±S.E.M. * p < 0.05 compared with sham group, #non-significant difference from IR group, $p < 0.05 compared with IR group.