Figure 1: Effect of pretreatment with diacerein (5, 10mg/kg) on (a): serum levels of AST, ALT and LDH. (b): tissue levels of TNF-α, IL-6 and IL-1β in rats subjected to IR liver injury. Data represent means ± S.E.M. *p<0.05 compared with sham group, # non-significant difference compared with IR group, $p<0.05 compared with IR group.